Ethiopia stunned six-time African champions Egypt with a 2-0 win in 2023 Africa Cup of Nations qualifying.
Elsewhere on Thursday Morocco, Nigeria, Mali and Guinea Bissau all had to come from behind to win their games.
Cameroon began their qualifying campaign with a narrow victory over Burundi while Guinea left it very late for to overcome Malawi.
Minnows Lesotho held the 2023 hosts Ivory Coast to a goalless draw and register their first point of the qualifiers.
Group D wide open
Playing without injured captain Mohamed Salah Egypt were shocked by Ethiopia, who won the Group D encounter 2-0.
Dawa Hotessa gave Ethiopia the lead after 21 minutes and then hit the woodwork soon after and then had a goal ruled out for offside.
The Ethiopians did add to their tally just before half-time as Egypt-based Shimelis Bekele was on target.
Despite having more of the possession the Pharaohs managed just three shots, only one of which was on target, which all came in the second-half.
The game was played in Malawi as Ethiopia do not have a stadium that can host international fixtures
Guinea left it very late to beat visitors Malawi in the other Group D game with Liverpool’s Naby Keita scoring the only goal of the game in injury time at the end of the match.
All four teams in the group now have three points each after the opening two rounds of fixtures.